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Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide, Hypoallergenic No Added Parabens & Dyes, Protects & Relieves Baby’s Skin for Up to 12 Hours, Prevents Diaper Rash, 4.8 oz Tube

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Availability: In Stock.
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Arrives Friday, Aug 14
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Size: 4.8 Ounce (Pack of 1)


Features

  • Maximum Strength Diaper Rash Cream: Desitin diaper cream contains 40% zinc oxide to treat and prevent diaper rash on contact, sealing out wetness and forming a protective barrier that soothes delicate baby skin for up to 12 hours
  • Rich, Thick Paste Formula: Hypoallergenic, with no added parabens and dyes. This diaper rash cream is dermatologist and pediatriciantested for safe daily use, providing gentle yet effective soothing relief and fast healing after each diaper c
  • 5-in-1 Soothing Action: Clinically proven to treat, heal, protect, soothe and help prevent diaper rash, this maximum strength paste seals out wetness and soothes chafed skin for noticeable relief after 1 use
  • Targeted Care: This moisture-locking paste quickly relieves chafed skin on babys bottom, keeping skin dry and comfortable between diaper changes. Best for stubborn, persistent irritation.
  • Easy, All-Day Application: Apply liberally at each diaper change, especially before bedtime or extended wear, for continuous protection and relief, making Desitin diaper rash cream a trusted staple in baby skincare

Description

Desitin Maximum Strength Baby Diaper Rash Cream features a rich, thick paste with 40% maximum-level zinc oxide to treat and help prevent baby diaper rash discomfort. Clinically shown to protect delicate baby skin for up to 12 hours, this dermatologist and pediatriciantested diaper cream forms a durable, water- resistant barrier that seals out wetness, soothes irritation on contact, and helps protect chafed skin. The hypoallergenic formula is gentle enough for daily use and is free of parabensand dyes. Delivering 5-in-1 action to treat, heal, protect, soothe, and prevent diaper rash, it supports immediate relief while keeping your baby comfortable day and night. If you’re searching for a diaper rash cream baby parents can rely on, this baby diaper cream paste provides targeted coverage that stays in place between changes, including overnight. For best results, cleanse and thoroughly dry the diaper area, then apply a thick layer to fully cover affected skin; reapply liberally with each diaper change, especially at bedtime or anytime exposure to a wet diaper may be prolonged. For prevention, use at each change on healthy skin in areas prone to moisture and friction. Available in a convenient 4.8-ounce tube that fits easily in diaper bags, this essential diaper cream is designed for at- home and on-the-go care. Note: The rich, protective paste may transfer to fabrics and leave a white residue; to help remove, pretreat and launder with warm water and mild detergent. Some users notice a mild, natural scent. Add Desitin Maximum Strength paste to your baby care routine to help protect delicate skin and maintain consistent comfort between changes. This maximum- strength diaper paste formulated with 40% zinc oxideand a thick, creamy texture spreads evenly to create a long-lasting barrier, making it a dependable choice for treatment and daily protection for your baby diaper care routine.

Brand: Desitin


Item Form: Cream


Item Weight: 4.8 Ounces


Age Range (Description): Baby


Active Ingredients: Zinc Oxide


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 1.69 x 2.38 x 6.94 inches; 4.8 ounces


Item model number ‏ : ‎ 3423


Date First Available ‏ : ‎ October 17, 2014


Manufacturer ‏ : ‎ Kenvue


Best Sellers Rank: #9 in Baby (See Top 100 in Baby) #1 in Diaper Creams


#1 in Diaper Creams:


Customer Reviews: 4.8 4.8 out of 5 stars (47,855)


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Friday, Aug 14

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • A household essential that heals fast and protects even better
Size: 16 Ounce (Pack of 1)
A household essential that heals fast and protects even better Desitin Maximum Strength Diaper Rash Cream has been around for decades for a reason—it simply works. The 40% zinc oxide formula is thick, soothing, and forms an instant protective barrier that seals out moisture and promotes healing. It’s the go-to for stubborn rashes that other creams can’t touch, often clearing irritation within a day or two. The cream’s texture is dense but spreads evenly, staying in place through multiple diaper changes or overnight use. It’s gentle enough for newborns yet strong enough for adults dealing with chafing or skin irritation from incontinence pads, sweat, or friction. Because it’s hypoallergenic and free of parabens, phthalates, and dyes, it rarely causes irritation even on sensitive skin. The 16-ounce tub is great value—it lasts for months and is far more economical than small tubes. The only minor drawback is that the paste can be hard to remove completely from skin or fabric if overapplied, and it has a mild medicinal scent that not everyone loves. Bottom line: a trusted, dermatologist-tested classic that lives up to its reputation. If you need fast, reliable relief for diaper rash, chafing, or general skin irritation, Desitin Maximum Strength remains the gold standard for both babies and adults alike. ... show more
Reviewed in the United States on October 19, 2025 by Everyday Reviews

  • Always reliable
Size: 16 Ounce (Pack of 1)
This is a staple in our household because it really creates a thick barrier that protects the skin. It works faster than most other brands I’ve tried, and you can usually see an improvement by the next morning. I’m giving it 4 stars because, while the thickness is what makes it effective, it is quite difficult to wash off your hands after applying it. It’s also a bit messy if it gets on clothes, but in terms of healing a stubborn rash, it’s definitely one of the most reliable products out there ... show more
Reviewed in the United States on January 27, 2026 by Mario Enrique Hernández

  • Great time-tested remedy. Cheaper at Walmart.
Size: 4.8 Ounce (Pack of 1)
This is great stuff and often the only thing that works for minor annoying thingies. My dermatologist 's recommendation . However, Walmart has their own brand of 40% zinc oxide (which is what this is) at 1/5th the price. Ah, the price of advertising.
Reviewed in the United States on January 15, 2026 by HHCCAZ

  • Thick
Size: 4.8 Ounce (Pack of 1)
Works exactly how it should. Thick, protective ointment that stops and soothes diaper rash fast. A little goes a long way, doesn’t sting, and stays put through messy changes. Reliable diaper-bag staple every parent should have.
Reviewed in the United States on January 15, 2026 by Shosh

  • Simply excellent
Size: 16 Ounce (Pack of 1)
-Desitin Maximum Strength Paste is a staple for our baby’s sensitive skin. The 40% zinc oxide formula provides an excellent protective barrier that isn’t too thick. In our experience, it makes rashes disappear in 1-2 uses. It is extremely reliable and we don’t leave the house without it. We prefer this concentration to the 13% zinc oxide (blue label). We don’t leave the house without it and the 16oz tub provides excellent value. ... show more
Reviewed in the United States on January 5, 2026 by Seth M.

  • Good quality product
Size: 16 Ounce (Pack of 1)
Excellent, does the job of preventing diaper rashes. We bought it after the diaper rash started and it helped the skin heal
Reviewed in the United States on February 15, 2026 by Amazon Customer

  • good ole diaper cream
Size: 16 Ounce (Pack of 1)
gets the job done, but the cod liver oil smell is so strong
Reviewed in the United States on February 17, 2026 by Stephanie

  • Great Product
Size: 16 Ounce (Pack of 1)
Works great! Way thicker than the normal stuff and last a lot longer. I like having the jar on the changing table. Easier to get when you only have one hand available.
Reviewed in the United States on February 13, 2026 by Amazon Customer

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